1College of Korean Medicine, Wonkwang University, Iksan, Republic of Korea
2Department of Diagnostics, College of Korean Medicine, Wonkwang University, Iksan, Republic of Korea
3Research Center of Traditional Korean Medicine, College of Korean Medicine, Wonkwang University, Iksan, Republic of Korea
4Department of Il-Won Integrated Medicine, Wonkwang University Korean Medicine Hospital, Iksan, Republic of Korea
5Cham Kyung-hee Korean Medicine Clinic, Seoul, Republic of Korea
6Ansim Korean Medicine Clinic, Incheon, Republic of Korea
©2025 Jaseng Medical Foundation
This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Author Contributions
Writing-original draft preparation: JK and DP. Writing-review & editing: HJ, JL, HL, and CA. Data curation: JK and DP. Investigation: DP. Methodology: HJ and JL. Supervision: HJ and JL. Funding acquisition: JL. Resources: HL. Conceptualization: HL and DP. Project administration: JL and DP.
Conflicts of Interest
The authors have no conflicts of interest to declare.
Author Use of AI Tools Statement
The authors used ChatGPT (OpenAI) solely for grammar and language improvement during the revision of this manuscript. The AI tool did not contribute to the scientific content, data analysis, or interpretation. The authors take full responsibility for all content.
Funding
This work was supported by a National Research Foundation of Korea grant (RS-2022-NR072366) and the Bio & Medical Technology Development Program of the National Research Foundation funded by the Korean government (MSIT) (no. RS-2023-00261934). This research was also supported by a grant of the Korea Health Technology Project through the Korea Health Industry Development Institute, funded by the Ministry of Health and Welfare, Republic of Korea (grant no. RS-2025-02221762).
Ethical Statement
This case report is based on the patient’s medical records and received an exemption from the Institutional Review Board of Wonkwang University (no.: WKIRB-202409-BM-068).
Herbal name | Pinyin name | Daily dosage (g) |
---|---|---|
Yixin Tang (Iksim-tang) 45 packs (15-d supply, shipped on Day 1) | ||
| ||
Salviae miltiorrhizae Radix | Danshen | 12 |
Codonopsis pilosula Radix | Dangshen | 10 |
Astragali Radix | Huangqi | 10 |
Liriope seu Ophiopogonis Tuber | Maimendong | 10 |
Galli Gigeriae Endothelium Corneum | Jineijin | 8 |
Schisandrae Fructus | Wuweizi | 8 |
Longan Arillus | Longyanrou | 8 |
Thujae Semen | Baiziren | 8 |
Allii Macrostemonis Bulbus | Xiebai | 8 |
Puerariae Radix | Gegen | 8 |
Pinelliae Tuber Praeparatum cum Zingibere | Jiangzhi Banxia | 6 |
Trichosanthis Semen | Gualouren | 6 |
| ||
Modified Banxia Houpo Tang (Gamibanhahubak-tang) 45 packs (15-d supply, shipped on Day 21) | ||
| ||
Pinelliae Tuber Praeparatum cum Zingibere | Jiangzhi Banxia | 10 |
Codonopsis pilosula Radix | Dangshen | 8 |
Salviae miltiorrhizae Radix | Danshen | 8 |
Poria Sclerotium | Fuling | 8 |
Perillae Folium | Suye | 6 |
Citri Unshius Pericarpium | Chenpi | 6 |
Magnoliae Cortex | Houpo | 6 |
Thujae Semen | Baiziren | 6 |
Liriopis seu Ophiopogonis Tuber | Maimendong | 6 |
Schisandrae Fructus | Wuweizi | 6 |
Zingiberis Rhizoma Recens | Shengjiang | 4 |
Zizyphi Fructus | Dazao | 4 |
Glycyrrhizae Radix et Rhizoma | Gancao | 4 |
Aurantii Fructus Immaturus | Zhiqiao | 3 |
| ||
Jupi Zhuru Tang (Gyulpijukyeo-tang) 45 packs (15-day supply, shipped on Day 56) | ||
| ||
Zizyphi Fructus | Dazao | 20 |
Citri Reticulatae Pericarpium | Jupi | 16 |
Zingiberis Rhizoma Recens | Shengjiang | 16 |
Glycyrrhizae Radix et Rhizoma | Gancao | 10 |
Phyllostachyos Caulis in Taeniam | Zhuru | 8 |
Codonopsis Pilosulae Radix | Dangshen | 6 |
B.I.D = twice a day; HM = herbal medicine; NRS = numerical rating scale; NT-proBNP = N-terminal prohormone of brain natriuretic peptide; T.I.D = three times a day.