Perspectives on Integrative Medicine

Protocols

Artificial Intelligence in the Editorial and Peer Review Process: A Protocol for a Cross-Sectional Survey of Traditional, Complementary, and Integrative Medicine Journal Editors’ Perceptions: Jeremy Y. Ng, Daivat Bhavsar, Neha Dhanvanthry, Myeong Soo Lee, Ye-Seul Lee, Tanuja M. Nesari, Thomas Ostermann, Claudia M. Witt, Linda Zhong, Holger Cramer; Perspect Integr Med. 2025;4(2):121-124. Published online June 23, 2025; DOI: https://doi.org/10.56986/pim.2025.06.008

2,194 View
38 Download

Graphical Abstract Abstract PDF Supplementary Material: This research protocol outlines a cross-sectional survey study, aimed at editors from traditional, complementary, and integrative medicine (TCIM) journals, regarding their perceptions of the use of artificial intelligence (AI) in the editorial and peer review process. The survey will be sent to editors-in-chief, associate editors, and editorial board members of TCIM journals (100-150). The research involves purposive sampling via manual collection of contact details from TCIM journal websites. The survey will include sections on demographics, current use and familiarity with AI, perceived benefits and challenges, ethical concerns, and the outlook for AI in publishing. Data collection will be conducted online using SurveyMonkey whereby email invitations and follow-up reminders will be sent to potential respondents. Quantitative data will be analyzed using descriptive statistics, and for qualitative data, thematic analyses will be employed. This protocol study aimed to devise a survey which could provide insight into the acceptance and potential barriers to AI adoption in TCIM publishing from an editor’s perspective. The results of which may later guide the development of AI tools in a way that aligns with the needs and values of the TCIM research community.

A Study Protocol for Developing a Consensus-Based Reporting Guideline for Case Reports on Acupuncture-Related Adverse Events: Tae-Hun Kim, Ye-Seul Lee, Jung-Won Kang, Myeong Soo Lee, Lin Ang, Jeremy Y. Ng, Stephen Birch, Terje Alræk, Lin Yu, Yuting Duan, Zhirui Xu; Perspect Integr Med. 2025;4(2):117-120. Published online June 23, 2025; DOI: https://doi.org/10.56986/pim.2025.06.007

1,302 View
28 Download

Graphical Abstract Abstract PDF Supplementary Material: Case reports play a crucial role in identifying safety concerns related to new or rare complications and adverse events (AEs) associated with therapeutic interventions. Although acupuncture is generally considered safe when performed by trained professionals, the increasing number of case reports reporting acupuncture-related AEs has raised public safety concerns. A recent systematic review of case reports from 2010 to 2023 determined that many reports lacked the essential details necessary for assessing AE causality, treatment appropriateness, and contributing risk factors. These omissions may result in misinformation, and exaggerate the potential harm of acupuncture. The CAse REport guidelines (13 items) provide general guidance to improve the clarity, completeness, and transparency of case report findings, but they do not address the unique clinical features and factors specific to acupuncture-related AEs such as defective needles, practitioner malpractice, or patient-related factors. These limitations may hinder the educational value of such reports in preventing acupuncture-related AEs. To address this gap, a consensus-based reporting guideline tailored to acupuncture-related AEs is necessary to enhance the quality, transparency, and reliability of case reports, which will ultimately contribute to improved patient care. This article outlines a protocol, and approaches, for developing a reporting guideline for acupuncture-related AEs in case reports.

Short Communication

Robust Evidence in Integrative Medicine: Innovations, Challenges, and Future Directions: Ye-Seul Lee, Myeong Soo Lee, David Moher, In-Hyuk Ha, Jian-Ping Liu, Terje Alræk, Stephen Birch, Tae-Hun Kim, Yoon Jae Lee, Juan V.A. Franco, Jeremy Y. Ng, Holger Cramer; Perspect Integr Med. 2024;3(3):162-167. Published online October 23, 2024; DOI: https://doi.org/10.56986/pim.2024.10.005

3,773 View
65 Download

Graphical Abstract Abstract PDF: Integrative Medicine (IM), which includes therapies such as acupuncture, herbal medicine, yoga, and meditation, is gaining attention for managing chronic pain conditions. However, concerns about the quality of evidence supporting the use of these interventions persist. The 5th Annual Jaseng Academic conference 2024, in Seoul, South Korea, themed "Robust Evidence in Integrative Medicine: Innovations, Challenges, and Future Directions," addressed these concerns by focusing on advancements in study design, evidence synthesis, and open science practices. This conference proceeding summarizes key insights from the conference, emphasizing the role of pragmatic randomized controlled trials (pRCTs) in evaluating real-world effectiveness, and addressing the complexities involved in IM research such as sham controls. The integration of IM therapies into comprehensive pain management strategies (particularly in Korea), supported by government-backed research and policy initiatives was also discussed. Advancements in methodologies were addressed, such as bibliometric analysis, evidence mapping, and the development of clinical practice guidelines (CPGs) for integrative therapies. These methodologies offer valuable insights but face challenges due to the heterogeneity of IM interventions, and potential synergistic or antagonistic effects when combined with conventional medicine. Finally, the potential of open science to enhance transparency, reporting, and reproducibility in IM was explored, emphasizing the increased role of adherence to reporting guidelines (CONSORT and PRISMA). The future of IM research is built upon the continued efforts of refined study designs, rigorous evidence synthesis, and the integration of open science principles, for a robust and more credible evidence base.

Review Article

Addressing the Challenges of Traditional, Complementary, and Integrative Medicine Research: An International Perspective and Proposed Strategies Moving Forward: Maheen Raja, Holger Cramer, Myeong Soo Lee, L. Susan Wieland, Jeremy Y. Ng; Perspect Integr Med. 2024;3(2):86-97. Published online June 21, 2024; DOI: https://doi.org/10.56986/pim.2024.06.004

27,543 View
312 Download
13 Citations

Graphical Abstract Abstract PDF

Traditional, complementary, and integrative medicine (TCIM) encompasses a broad range of healthcare practices beyond conventional Western medicine. Despite its use globally and increased research, many TCIM research challenges persist impeding its progress and integration into clinical practice. Key challenges involve financial constraints, insufficient research training and educational support, and the methodological barriers which arise from a lack of standardization. Financial limitations hinder investment into crucial research limiting both the quantity and quality of TCIM research. Inadequate training in research and educational support limit the development of TCIM research, hindering growth and recognition of TCIM in academic and clinical settings. The inherent dynamic nature of TCIM therapies poses additional challenges for applying standardized biomedical research models. These challenges not only impede the advancement of TCIM research but also perpetuate negative attitudes and biases within the healthcare and research communities. To overcome these challenges, a comprehensive strategy is necessary to increase funding, improve literacy, and the promotion of open science practices in TCIM. Addressing these confounding factors will enable well-informed TCIM research literacy and the development of TCIM skills and facilitate the integration of evidence based TCIM therapies into a more inclusive healthcare domain, ultimately reducing negative attitudes and biases towards TCIM.

Citations

Citations to this article as recorded by

“There is a way to work together”: A qualitative study on complementary medicine therapists' perceptions of their role in the Swiss healthcare system
Julie Dubois, Pierre-Yves Rodondi, Christina Akre
Complementary Therapies in Clinical Practice.2025; 58: 101919. CrossRef
The case for data sharing in traditional, complementary, and integrative medicine research
Jeremy Y. Ng
Integrative Medicine Research.2025; 14(1): 101101. CrossRef
Harnessing plant metabolic pathways for innovative diabetes management: unlocking the therapeutic potential of medicinal plants
Ugwu Okechukwu Paul-Chima, Anyanwu Chinyere Nkemjika, Ugwu Melvin Nnaemeka, Hope Onohuean
Plant Signaling & Behavior.2025;[Epub] CrossRef
Clinical outcomes and cost-effectiveness of collaborative treatment with Korean and Western medicine in patients with facial palsy: a multicenter prospective observational study
Shiva Raj Acharya, Linae Kim, NamKwen Kim
BMC Complementary Medicine and Therapies.2025;[Epub] CrossRef
Challenges and opportunities for integrating traditional healing approaches with biomedical care for mental illness: A scoping review from healers’ perspectives
Alemayehu Molla Wollie, Kim Usher, Kylie Rice, Md Shahidul Islam, Godwin Upoki Anywar
PLOS One.2025; 20(6): e0325353. CrossRef
Traditional alternative and complementary medicine: a review of undergraduate courses and curricula in Peru
Juan Huaccho-Rojas, Leonardo J. Uribe-Cavero, Angie Diaz-Mejía, Mabel R. Challapa-Mamani, Marisella Chumán-Sánchez, Oswaldo N. Vite-Gutierrez, Jeremy Yauri-Mamani, Omar C. Bellota-Segovia, Paula Regina Durand-Anahua, Yahaira M. Mamani-Ticona, Zulema Maman
Journal of Complementary and Integrative Medicine.2025;[Epub] CrossRef
Prompt engineering for generative artificial intelligence chatbots in health research: A practical guide for traditional, complementary, and integrative medicine researchers
Jeremy Y. Ng
Integrative Medicine Research.2025; 14(4): 101222. CrossRef
Management of symptoms of suspected adenomyosis uteri using herbal medicine modified Bojungikgi-tang: a case report with ultrasound monitoring
Hyunsuk Park, Hyein Jeong, Kyeong Han Kim, Seung Jeong Yang, Stella Roh
Frontiers in Medicine.2025;[Epub] CrossRef
Literature Review of Herbal Remedies Used for Diabetes Mellitus: Efficacy, Safety, and Regulatory Considerations
Nada M. Sonji, Ghassan M. Sonji
Jordan Journal of Pharmaceutical Sciences.2025; 18(3): 724. CrossRef
Exploring study materials and data sharing practices in traditional, complementary and integrative medicine research: a protocol for a cross-sectional study
Gabriela Melendez, Shahreen Rahman, Olena Zubrytska, Florian Naudet, Livia Puljak, Claudia M. Witt, Linda Lidan Zhong, David Moher, Holger Cramer, Jeremy Y. Ng
Evidence-Based Chinese Medicine and Technology Ass.2025; 1(2): 9570014. CrossRef
A Protocol for a Bibliometric Analysis of Traditional, Complementary, and Integrative Medicine Research Preprints
Jeremy Y. Ng, Brenda Lin, Sabrina Abdella, Magdalene Abebe, Isabella Tao, Holger Cramer
Perspectives on Integrative Medicine.2024; 3(3): 172. CrossRef
Robust Evidence in Integrative Medicine: Innovations, Challenges, and Future Directions
Ye-Seul Lee, Myeong Soo Lee, David Moher, In-Hyuk Ha, Jian-Ping Liu, Terje Alræk, Stephen Birch, Tae-Hun Kim, Yoon Jae Lee, Juan V.A. Franco, Jeremy Y. Ng, Holger Cramer
Perspectives on Integrative Medicine.2024; 3(3): 162. CrossRef
PRIO – a prospective integrative oncology registry: trial protocol
Paul G. Werthmann, Ann-Kathrin Lederer, Hannah Maja Figura, Klaus Kramer
Frontiers in Oncology.2024;[Epub] CrossRef

Letter

Treatment Recommendations in Korea for Patients with Axial Spondyloarthritis: The Evidence for Acupuncture Treatment in Axial Spondyloarthritis Patients Should be Re-evaluated: Tae-Hun Kim, Myeong Soo Lee, Hyangsook Lee, Stephen Birch, Terje Alraek; Perspect Integr Med. 2024;3(1):61-62. Published online February 22, 2024; DOI: https://doi.org/10.56986/pim.2024.02.009

2,965 View
24 Download

PDF

Short Communication

Perspectives and Ideas to Advance Integrative Medicine and Healthcare: Proceedings of the 4^th Annual Jaseng Academic Conference: Andrew Jang, Jinho Lee, Catherine Donahue, David Coggin-Carr, Mike Cummings, Kien Trinh, Myeong Soo Lee, Susan Wieland, Christopher Zaslawski, Lawrence Prokop, Joon Shik Shin; Perspect Integr Med. 2023;2(3):190-194. Published online October 23, 2023; DOI: https://doi.org/10.56986/pim.2023.10.007

2,944 View
32 Download
1 Citations

Abstract PDF

The 4^th Annual Jaseng Academic conference (August 13, 2023) in Seoul, South Korea, was a pivotal event in the realm of integrative medicine. Cohosted by Jaseng Hospital of Korean Medicine and Michigan State University College of Osteopathic Medicine, over 500 professionals including Korean medicine doctors, medical doctors, doctors of osteopathic medicine, acupuncturists, researchers, and students gathered at the conference. The theme, “Perspectives on Integrative Medicine,” marked a departure from previous conference themes and embraced a multidisciplinary approach to healthcare. The event highlighted the importance of holistic patient care and cross-disciplinary collaboration within healthcare. It offered a comprehensive overview of the current state of integrative medicine approaches in manual medicine, evidence-based acupuncture treatment, and acupuncture research. The Annual Jaseng Academic conference continues to serve as a platform for healthcare professionals to exchange ideas and perspectives, and bridges the gap between diverse medical systems to promote improved patient outcome and wellbeing.

Citations

Citations to this article as recorded by

Effects of Combined Shinbaro and Celecoxib in a Complete Freund’s Adjuvant-Induced Inflammatory Pain Mouse Model
Jae-Hwan Jang, Yurim Song, Seok Hee Han, Bo Ram Choi, Yoon Jae Lee, In-Hyuk Ha
Journal of Inflammation Research.2025; Volume 18: 2349. CrossRef

Guideline

ACURATE: A Guide for Reporting Sham Controls in Trials Using Acupuncture: Ye-Seul Lee, Song-Yi Kim, Hyangsook Lee, Younbyoung Chae, Myeong Soo Lee; Perspect Integr Med. 2023;2(2):100-106. Published online June 23, 2023; DOI: https://doi.org/10.56986/pim.2023.06.004

3,518 View
29 Download
1 Citations

Abstract PDF

This paper presents the Acupuncture Controls gUideline for Reporting humAn Trials and Experiments (ACURATE) checklist, an extension of The Consolidated Standards for Reporting of Trials (CONSORT) and to be used along with STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) when both real and sham acupuncture needles are used in the study. This checklist focuses on a clear depiction of sham needling procedures to enhance replicability and enable a precise appraisal. We encourage researchers to use ACURATE in trials and reviews involving sham acupuncture to assist reporting of sham acupuncture procedures and the related components.

Citations

Citations to this article as recorded by

Robust Evidence in Integrative Medicine: Innovations, Challenges, and Future Directions
Ye-Seul Lee, Myeong Soo Lee, David Moher, In-Hyuk Ha, Jian-Ping Liu, Terje Alræk, Stephen Birch, Tae-Hun Kim, Yoon Jae Lee, Juan V.A. Franco, Jeremy Y. Ng, Holger Cramer
Perspectives on Integrative Medicine.2024; 3(3): 162. CrossRef

Protocol

A Protocol for the Overview of Systematic Reviews of Aromatherapy for Management of Health: Ki Jung Kil, Myeong Soo Lee; Perspect Integr Med. 2023;2(1):56-58. Published online February 21, 2023; DOI: https://doi.org/10.56986/pim.2023.02.008

6,354 View
61 Download

Abstract PDF: Background
Aromatherapy has been reported to have a positive effect on various health conditions. While these studies show positive results, many of them have limited evidence. The aim of this study was to develop a protocol to evaluate all systematic reviews (SRs) that have evaluated the efficacy of aromatherapy (for any health condition) as a therapeutic treatment (protocol registration number INPLASY202280089).
Methods
We will include aromatherapy through different therapeutic application methods such as inhalation, massage, and bathing. Seven international databases (including PubMed, AMED, EMBASE, the Cochrane Library), and three Korean medical databases (Korean Studies Information, Research Information Service System, KoreaMed), will be searched. The SR process, including study selection, data extraction, and assessment, will be performed by two independent reviewers. Methodological assessment will be performed using AMSTAR-2.
Discussion
The benefits of aromatherapy for health management are evaluated to provide useful information to patients and therapists and inform decisions on further studies on this topic.

Review Article

Shoulder Pain and the Potential Role of Acupuncture: A Narrative Review of Clinical Practice and Treatment Guidelines: Stephen Birch, Myeong Soo Lee, Tae-Hun Kim, Terje Alraek; Perspect Integr Med. 2022;1(1):3-9. Published online September 22, 2022; DOI: https://doi.org/10.56986/pim.2022.09.002

14,662 View
189 Download
4 Citations

Abstract PDF Supplementary Material

The potential use of acupuncture for shoulder pain of various etiologies and whether clinicians make recommendations about the use of acupuncture was examined. Shoulder pain is a common clinical problem. What is the level of evidence and how often is acupuncture recommended for shoulder pain? A manual and database (PubMed) search of review articles of related clinical trials and guidelines was performed. The evidence for effectiveness of acupuncture treatment of different types of shoulder pain was weak. However, there are some studies, with a weak to moderate level of evidence, on shoulder pain (across nine subtypes of shoulder pain). Acupuncture is safe and may be a cost-effective treatment for shoulder pain. There were 131 statements recommending the use of acupuncture for shoulder pain across 12 subtypes of shoulder pain. The most common statements were for non-specific ‘shoulder pain.’ There were 11 statements against the use of acupuncture for shoulder pain and three subtypes of shoulder pain. The level of evidence in studies of acupuncture treatment for shoulder pain is low, therefore, further research is needed. Recommendations for the use of acupuncture for shoulder pain are increasing but lag behind those for other pain problems such as low back pain.

Citations

Citations to this article as recorded by

“Are we there yet?” – Green shoots of progress in acupuncture implementation in healthcare
Sandro Graca, Matthias Huemer, Beverley de Valois, Bobbee Vang, Lara McClure
European Journal of Integrative Medicine.2024; 69: 102371. CrossRef
Health Care Utilization for Common Shoulder Disorders: Analysis of the 2010–2019 National Patient Sample Data from the Health Insurance Review and Assessment Service in Korea
Jin-Young Kang, Doori Kim, Huijun Kim, In-Hyuk Ha, Yoon Jae Lee
Medicina.2024; 60(5): 744. CrossRef
Clinical effect analysis of timed strengthening moxibustion combined with continuing nursing on symptoms of qi deficiency and blood stasis type
Fang Liu, Xuan Wang, Man Zhao, Qing Qin
Medicine.2024; 103(52): e40886. CrossRef
A Review of Key Research and Engagement in 2022
John McDonald, Sandro Graca, Claudia Citkovitz, Lisa Taylor-Swanson
Journal of Integrative and Complementary Medicine.2023; 29(8): 455. CrossRef

First
Prev
Page of 1
Next
Last

Search