Skip Navigation
Skip to contents

PIM : Perspectives on Integrative Medicine


Most read

Page Path
HOME > Articles and issues > Most read
6 Most read
Article category
Publication year
Funded articles

Most-read articles are from the articles published in 2020 during the last three month.

Review Article
Effects of Acupuncture on Neuropathic Pain: Mechanisms in Animal Models
Jae-Hwan Jang, Hi-Joon Park
Perspect Integr Med. 2022;1(1):17-20.   Published online September 22, 2022
  • 411 View
  • 16 Download
AbstractAbstract PDF
Neuropathic pain is a chronic condition/disease characterized by mechanical and thermal pain. Neuropathic pain can have various comorbidities such as depression, anxiety disorders and cognitive impairment, and as a result, can have a detrimental effect on quality of life. Pain and comorbid symptoms are often complicated, intertwined, affect each other, and present difficulties in treatment. Therefore, it is necessary to improve both pain and comorbid symptoms to treat neuropathic pain. Acupuncture is effective in treating not only pain but other conditions/diseases such as depression, anxiety, and cognitive impairment. Recently, acupuncture was reported to be effective in improving comorbid symptoms in patients with chronic pain. This review aimed to describe the mechanisms of action of acupuncture on the brain with respect to the improvement of comorbid symptoms that appeared in animal models of chronic neuropathic pain. Comorbidity-pain studies were comprehensively reviewed. Both manual acupuncture and electroacupuncture improved not only mechanical and thermal pain but also comorbid symptoms such as depression, anxiety, and cognitive impairment in patients with chronic neuropathic pain. The results of this review suggest that comorbid symptoms can be improved through various mechanisms, including the dopamine system in the brain, glutamate system, inflammation, epigenetic modulation, and mitochondrial function.
Original Article
An Overview of Clinical Features, and Medical Access Among Patients with Post-Acute COVID-19 Syndromes: Analysis of a Nationwide Survey in Korea
Doori Kim, Ui Min Jerng, Jee Young Lee
Perspect Integr Med. 2022;1(1):21-33.   Published online September 22, 2022
  • 336 View
  • 24 Download
AbstractAbstract PDFSupplementary Material
The objective of this study was to identify the clinical features of patients who recovered from COVID-19, and to determine their unmet medical needs and quality of life.
A cross-sectional national survey was conducted in Korea in June 2022, targeting patients with at least four weeks of symptoms of COVID-19. The questionnaire survey had 37 items across: basic characteristics, acute COVID-19 and post-acute COVID-19 syndrome (long COVID) symptoms, access to medical facilities for long COVID, unmet medical needs, long COVID support system, and quality of life.
Among 1,430 responses, 745 (52.1%) respondents had experienced long COVID. The most common symptoms were ear, nose, and throat complications (n = 461, 61.9%), followed by weakness and fatigue (n = 393, 52.8%). Amongst the 745 respondents who experienced long COVID, 337 (45.2%) had visited a medical institution, of which, 84.9% had visited a clinic or hospital for treatment. Korean medicine clinics and hospitals had the highest satisfaction rates (43.4%). There were 242 respondents (32.5%) who reported unmet medical needs for their long COVID. Symptom severity and duration of COVID-19 were risk factors for unmet medical needs. Quality of life was low in those patients with long COVID and unmet medical needs, and decreased further with increased severity and longer duration of symptoms.
Studies on the effects of Korean medicine treatment of long COVID, and establishing a system providing sufficient treatment for patients with long COVID are needed. These findings could be used by clinicians, researchers, and COVID-19-related policymakers.
Review Articles
Expanding the Scope of Manual Medicine Through Research, Academic Exchange, and Healthcare Coverage: A Summary of Two International Conferences
Seung Min Kathy Lee, Su-Bin Han, Boyd Buser, Kendi Hensel, Brian Kim, William Mayo, Nicola Robinson, Byung-Cheul Shin, Daniel Williams, Joon-Shik Shin, Me-riong Kim, In-Hyuk Ha, Jinho Lee, Lawrence Prokop
Perspect Integr Med. 2022;1(1):10-16.   Published online September 22, 2022
  • 334 View
  • 34 Download
AbstractAbstract PDF
In Korea, Chuna was officially included in the Korean national health insurance (NHI) system in 2019. In the US, osteopathic manipulative treatment has been part of conventional healthcare since 1966. Since there are few countries that provide manual therapy in mainstream healthcare, academic exchange between experts in Chuna therapy on an international stage is essential; to date there has been a conference in 2018 and 2019, both of which were held in Korea. This review presents a summary of these conference proceedings. There were 13 keynote speakers including doctors of Korean medicine, osteopathic physicians, and policymakers. In the 1st conference, seven speakers shared their knowledge on the history of Chuna, policies, and the current body of evidence for using Chuna and osteopathic manipulative treatment of various conditions. In the following year, six speakers also included novel Chuna techniques, similarities and differences, and explored the possibilities for collaborations moving forward. Previous to these two international conferences, the last national conference was held in Korea in 2008. The timing of these two international conferences has proved significant due to the inclusion of Chuna in Korean national health insurance in 2019, and helped to provide guidance in expanding the scope of manual medicine.
Shoulder Pain and the Potential Role of Acupuncture: A Narrative Review of Clinical Practice and Treatment Guidelines
Stephen Birch, Myeong Soo Lee, Tae-Hun Kim, Terje Alraek
Perspect Integr Med. 2022;1(1):3-9.   Published online September 22, 2022
  • 306 View
  • 41 Download
AbstractAbstract PDFSupplementary Material
The potential use of acupuncture for shoulder pain of various etiologies and whether clinicians make recommendations about the use of acupuncture was examined. Shoulder pain is a common clinical problem. What is the level of evidence and how often is acupuncture recommended for shoulder pain? A manual and database (PubMed) search of review articles of related clinical trials and guidelines was performed. The evidence for effectiveness of acupuncture treatment of different types of shoulder pain was weak. However, there are some studies, with a weak to moderate level of evidence, on shoulder pain (across nine subtypes of shoulder pain). Acupuncture is safe and may be a cost-effective treatment for shoulder pain. There were 131 statements recommending the use of acupuncture for shoulder pain across 12 subtypes of shoulder pain. The most common statements were for non-specific ‘shoulder pain.’ There were 11 statements against the use of acupuncture for shoulder pain and three subtypes of shoulder pain. The level of evidence in studies of acupuncture treatment for shoulder pain is low, therefore, further research is needed. Recommendations for the use of acupuncture for shoulder pain are increasing but lag behind those for other pain problems such as low back pain.
Original Article
Current Status of Korean Medicine Treatment for Post-acute COVID-19 Syndrome: A Survey of Korean Medicine Doctors
Doori Kim, Seo-Hyun Park, Won-Suk Sung, Eun-Jung Kim
Perspect Integr Med. 2022;1(1):34-44.   Published online September 22, 2022
  • 209 View
  • 20 Download
AbstractAbstract PDFSupplementary Material
The applicability of Korean medicine (KM) treatments for post-acute COVID-19 syndrome were investigated.
A cross-sectional, web-based survey of Korean medical doctors (KMDs) was conducted in June 2022. The 25-item questionnaire comprised of five parts: basic characteristics, prescribed post-COVID-19 KM treatments, treatment effect in patients with post-acute COVID-19 syndrome, patient satisfaction, and awareness and utilization of the relevant KM Clinical Practice Guideline by the KMDs.
In total, 1,063 completed questionnaires were collected, and 822 were analyzed. The most common symptoms in patients with post-acute COVID-19 syndrome treated by KMDs was weakness and fatigue (84.3%). Herbal decoctions (39.2%) and herbal powder (not covered by medical insurance; 25.8%) were primarily used. Among the KMDs, 95% (n = 781) responded that KM treatments, particularly herbal decoctions (82.6%) and herbal powder (not covered by medical insurance; 46.8%), were effective. Overall, 92.6% (n = 761) of KMD participants answered that the patients were satisfied with KM treatments, mostly due to symptomatic improvement (60.8%). The primary reason for dissatisfaction was the burden of cost for patients (78.4%). The main reasons for low uptake of KM services by patients with post-acute COVID-19 syndrome were lack of publicity and administrative issues such as no health insurance coverage.
KM is highly applicable for post-acute COVID-19 syndrome. Health policies supporting the use of KM for post-acute COVID-19 syndrome are recommended.
Expanding Perspectives on Integrative Medicine: Promoting Global Health in the COVID-19 Era
Joon-Shik Shin
Perspect Integr Med. 2022;1(1):1-2.   Published online September 22, 2022
  • 239 View
  • 29 Download

PIM : Perspectives on Integrative Medicine